University of California, Riverside

Cheng Research Lab

Research Areas

Biosensor Technology Interests

Our research is broadly based on the design and fabrication of novel sensors and sensor arrays for biological molecules and agents, in particular bacterial protein toxins, peptides, and microbes. The multidisciplinary research carried out in our group encompasses aspects of molecular recogntion, supramolecular assembly, charge transfer, optical and impedance spectroscopy, voltammetry, and microfluidics. Major areas of interest include biosensor/arrays based on self-assembled monolayer or supported bilayers which mimic cell surface interactions, functional materials for analytical purposes synthesized by using principles of supramolecular chemistry, and surface plasmon resonance (SPR) for label-free detection of protein toxins.

Surface Plasmon Resonance Spectroscopy and Imaging

 Matt SPR schematic

Surface-Based Mass Spectrometry Chip Development

calcinated AuNP array

Biomimetic Membranes for Sensor Development and Biophysical Studies


Electrospun Nanofiber Sensors

Andy nanofiber TOC